Off Label Use of Cialis - Yes, Women Can Take it Too!

Primarily designed and FDA-approved for men with erectile dysfunction (ED), clinical trials have explored both the potential risks and benefits of the off-label use of Cialis for women.

Erectile Dysfunction in men is a known indicator of underlying peripheral vascular disease, cerebrovascular disease, or cardiovascular disease which increases their risk of stroke and heart attack. Cardiovascular disease in women parallels the risk in men. Women’s cardiovascular systems are partially protected by their reproductive hormones until they reach menopause. Early initiation of menopausal hormone therapy within 10 years of menopause further reduces their cardiovascular disease risk. However, along with hormone therapy, a daily dose of Cialis may also reduce or mitigate cardiovascular risk.

In addition to the cardiovascular benefits of Cialis for women, the sexual benefits are also significant. Some of the sexual benefits of Cialis for women include improved sexual arousal, enhanced vaginal lubrication, and stronger orgasms. Beyond the physical aspects, Cialis can help boost confidence and reduce the psychological stress associated with female sexual dysfunction.

Understanding the safety profile of Cialis is paramount prior to use.  While Cialis is generally well tolerated, potential side effects for women can include headache, indigestion, back pain, muscle aches, flushing and nasal congestion. Additionally, the dosage should be tailored to the individual, factoring in overall health, the presence of any sexual dysfunction, and specific needs. Cialis can also interact with various medications, including nitroglycerin, alpha blockers for blood pressure and certain CYP3A4 inhibitors.  Therefore, caution is used when prescribing to avoid adverse interactions.

The growing research of Cialis is encouraging women to be proactive towards their sexual health, exploring available options while seeking professional medical advice to navigate their journey safely and effectively. In addition to Cialis, there is now an FDA-approved peptide for Female premenopausal women with acquired or generalized hypoactive sexual desire disorder (HSDD). 

If you are interested in treatment, please call our office 321-338-7373 or schedule an appointment online at https://provider.kareo.com/kristen-laurella so that we can determine if you are an appropriate candidate for therapy and discuss all treatment options with you.

References: 

• Ashton AK, Weinstein W. Tadalafil reversal of sexual dysfunction caused by serotonin enhancing medications in women. J Sex Marital Ther. 2006 Jan-Feb;32(1):1-3. DOI: 10.1080/00926230500229079. PMID: 16234221.
• Bartlik, B., Sugarman, A., Seenaraine, S., & Green, S. FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire/Function in Women. Online Journal of Complementary & Alternative Medicine. 2020. DOI: 10.33552/OJCAM.2020.04.000578
• Cipriani S, Simon JA. Sexual Dysfunction as a Harbinger of Cardiovascular Disease in Postmenopausal Women: How Far Are We? J Sex Med. 2022 Sep;19(9):1321-1332
• Faubion, SS Rullo, JE. Sexual Dysfunction in Women: A Practical Approach.  Am Fam Physician. 2015;92(4):281-288.  https://www.aafp.org/pubs/afp/issues/2015/0815/p281.html
• Jaafarpour M, Khani A, Khajavikhan J, Suhrabi Z. Female sexual dysfunction: prevalence and risk factors. J Clin Diagn Res. 2013 Dec;7(12):2877-80. doi: 10.7860/JCDR/2013/6813.3822. Epub 2013 Dec 15. PMID: 24551663; PMCID: PMC3919309.